Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403728 | 0.85 | — | — | |
| SCHEMBL78355 | 0.83 | KDM4E (0.59) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL36169 | 0.83 | DNM1 (0.55) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL24485546 | 0.81 | DNM1 (0.63) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL794226 | 0.81 | DNM1 (0.53) | DNM1KDM4EPAOXHPGDPOLB | |
| Hydrochloric Acid SCHEMBL10730965 | 0.81 | DNM1 (0.53) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL427283 | 0.81 | KDM4E (0.61) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL7305937 | 0.79 | DNM1 (0.52) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL6357770 | 0.79 | DNM1 (0.52) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL24102742 | 0.79 | DNM1 (0.52) | DNM1KDM4EPAOXHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296225-A1 | CARBAMOYLOXYLABDANES | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-12-28 | — | — | EP | disclosed |
| WO-1988005047-A1 | CARBAMOYLOXYLABDANES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-07-14 | — | — | WO | disclosed |