Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL885320 | 0.93 | KDM4E (0.65) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL23171099 | 0.92 | KDM4E (0.65) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL28958163 | 0.91 | KDM4E (0.70) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL16303439 | 0.91 | KDM4E (0.70) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL12282948 | 0.91 | KDM4E (0.70) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL25478737 | 0.90 | KDM4E (0.61) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL11456594 | 0.86 | KDM4E (0.61) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL426172 | 0.85 | — | — | |
| SCHEMBL15217208 | 0.84 | KDM4E (0.58) | KDM4EMAPK1HIF1ADNM1PAOX | |
| SCHEMBL36169 | 0.83 | DNM1 (0.55) | KDM4EDNM1PAOXHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611766-B | Amide coordination carboxylic acid inner salt anti-swelling agent and preparation method and application thereof | 陕西科技大学 | 2024-04-16 | — | — | CN | claimed |
| CN-117770273-A | Composite herbicide glyphosate and imidazolinone herbicide as well as preparation method and application thereof | 福建兴华农林高新技术研究所 | 2024-03-29 | — | — | CN | claimed |
| CN-116534964-A | Modified polyaluminum ferric chloride and preparation method and application thereof | 衡阳市建衡实业有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-115611766-A | Amide coordination carboxylic acid inner salt anti-swelling agent and preparation method and application thereof | 陕西科技大学 | 2023-01-17 | — | — | CN | claimed |
| CN-107698755-B | Cationic polymer and preparation method and application thereof | 四川大学 | 2021-03-30 | — | — | CN | claimed |
| EP-3080079-B1 | OXIDATION OF 2-MERCAPTOETHANOL | BASF SE (DE) | 2018-07-25 | — | — | EP | claimed |
| US-20160318860-A1 | OXIDATION OF 2-MERCAPTOETHANOL | BASF SE (DE) | 2016-11-03 | — | — | US | claimed |
| EP-3080079-A1 | OXIDATION OF 2-MERCAPTOETHANOL | BASF SE (DE) | 2016-10-19 | — | — | EP | claimed |
| WO-2015086565-A1 | OXIDATION OF 2-MERCAPTOETHANOL | BASF SE (DE) | 2015-06-18 | — | — | WO | claimed |
| US-8148537-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2012-04-03 | — | — | US | claimed |
| EP-2125736-B1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA AS (DK) | 2011-03-30 | — | — | EP | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | claimed |
| US-20090012126-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-01-08 | — | — | US | claimed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | claimed |
| US-20080139575-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2008-06-12 | — | — | US | claimed |
| US-20080132545-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2008-06-05 | — | — | US | claimed |
| WO-2008016643-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | claimed |
| WO-2006089874-A1 | BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONES | GPC BIOTECH AG (DE) | 2006-08-31 | — | — | WO | claimed |
| US-4057430-A | MEROCYANINE THIOHYDANTOIN SENSITIZERS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-11-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139575-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | KDM4E 3309/4885MAPK1 2764/4885HIF1A 3497/4885 |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | PDE4A, PDE4B, PDE3B | KDM4E 772/4885MAPK1 1745/4885HIF1A 2483/4885 |
| US-20160318860-A1 | OXIDATION OF 2-MERCAPTOETHANOL | HAO2, GPX4, SQOR | KDM4E 3249/4885MAPK1 2315/4885HIF1A 707/4885 |
| US-20080132545-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | KDM4E 3309/4885MAPK1 2764/4885HIF1A 3497/4885 |
| US-20090012126-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | KDM4E 3309/4885MAPK1 2764/4885HIF1A 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.