Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2102303 | 0.98 | DNM1 (0.50) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL78355 | 0.81 | KDM4E (0.59) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL36169 | 0.81 | DNM1 (0.55) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL24485546 | 0.79 | DNM1 (0.63) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL794226 | 0.79 | DNM1 (0.53) | DNM1KDM4EPAOXHPGDPOLB | |
| Hydrochloric Acid SCHEMBL10730965 | 0.79 | DNM1 (0.53) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL10608974 | 0.79 | DNM1 (0.53) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL427283 | 0.79 | KDM4E (0.61) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL7305937 | 0.77 | DNM1 (0.52) | DNM1KDM4EPAOXHPGDPOLB | |
| SCHEMBL24102742 | 0.77 | DNM1 (0.52) | DNM1KDM4EPAOXHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133878-B1 | NOVEL ISOLATES OF TRICHODERMA, FUNGICIDAL COMPOSITIONS CONTAINING SAID ISOLATES AND USE THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1990-03-14 | — | — | EP | claimed |
| US-4378367-A | INSECTICIDES; PESTICIDES; PROTECT-IVE COATINGS | FBC LIMITED (GB) | 1983-03-29 | — | — | US | claimed |
| US-10851073-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | ABBVIE INC. (US) | 2020-12-01 | — | — | US | disclosed |
| US-20050227956-A1 | Control of mold growth on wood | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-4146646-A | BIS-AMIDE FUNGICIDAL COMPOUNDS | FISONS LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851073-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | PTPN1, PTPN2, PTPN18 | DNM1 1707/4885KDM4E 2069/4885PAOX 352/4885 |
| US-20050227956-A1 | Control of mold growth on wood | ERG28, AKR7A2, DPM1 | DNM1 2486/4885KDM4E 314/4885PAOX 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.