Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609186 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL6593237 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL7830552 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL10610293 | 0.76 | MAOB (0.44) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL10610286 | 0.76 | MAOB (0.44) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL10611105 | 0.75 | PKM (0.42) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL10611107 | 0.75 | PKM (0.42) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL31260255 | 0.74 | MAOB (0.64) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL224979 | 0.74 | MAOB (0.64) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL10610343 | 0.73 | KDM4E (0.48) | ALDH1A1KDM4EMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271550-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988000197-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYE^´SZETI GYA^´R (HU) | 1988-01-14 | — | — | WO | disclosed |