Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610934 | 0.67 | ADAMTS5 (0.40) | KDRMEN1KMT2ATDP1ALOX15 | |
| SCHEMBL7292209 | 0.66 | KDR (0.43) | KDRMEN1KMT2ATDP1ALOX15 | |
| SCHEMBL9780125 | 0.63 | KDR (0.42) | KDRMEN1KMT2AALDH1A1KCNH2 | |
| SCHEMBL5834274 | 0.63 | KDR (0.41) | KDRMEN1KMT2ATDP1ALOX15 | |
| SCHEMBL2477193 | 0.62 | KDR (0.40) | KDRMEN1KMT2ATDP1ALOX15 | |
| SCHEMBL12101890 | 0.61 | ALDH1A1 (0.45) | KDRMEN1KMT2ATDP1ALOX15 | |
| SCHEMBL29698819 | 0.61 | HPGD (0.48) | MEN1KMT2ATDP1ALOX15ADAMTS5 | |
| SCHEMBL216973 | 0.61 | ACHE (0.56) | KDRMEN1KMT2ATDP1ALOX15 | |
| SCHEMBL69404 | 0.61 | HPGD (0.48) | MEN1KMT2ATDP1ALOX15ADAMTS5 | |
| SCHEMBL10196640 | 0.61 | MEN1 (0.43) | KDRMEN1KMT2ATDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271550-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988000197-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYE^´SZETI GYA^´R (HU) | 1988-01-14 | — | — | WO | disclosed |