SCHEMBL69404

SCHEMBL69404

O=C1CSc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.48
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 2/20 0.48
ACHE P22303 1/20 0.45
MAOB P27338 2/20 0.45
MIF P14174 1/20 0.45
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALOX15 P16050 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.42
S100A4 P26447 2/20 0.41
CDC25B P30305 2/20 0.40
MAOA P21397 2/20 0.40
IDO1 P14902 1/20 0.40
AKT1 P31749 1/20 0.40
SNCA P37840 1/20 0.40
MAP2K1 Q02750 1/20 0.40
PIN1 Q13526 1/20 0.40
EHMT2 Q96KQ7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29698819 1.00 HPGD (0.48) HPGDALDH1A1KDM4EACHEMAOB
Methane SCHEMBL1586454 0.98 HPGD (0.47) HPGDALDH1A1KDM4EACHEMAOB
SCHEMBL65679 0.91 MAOB (0.42) HPGDALDH1A1KDM4EACHEMAOB
SCHEMBL7417 0.77 VHL (0.56) HPGDALDH1A1KDM4EACHEMAOB
SCHEMBL29414923 0.77 VHL (0.56) HPGDALDH1A1KDM4EACHEMAOB
SCHEMBL13190451 0.76 ACHE (0.61) HPGDALDH1A1KDM4EACHEMAOB
SCHEMBL11877796 0.74 MEN1 (0.46) HPGDALDH1A1KDM4EMAOBMEN1
SCHEMBL87112 0.74 ALDH1A1 (0.41) HPGDALDH1A1KDM4EACHEMEN1
SCHEMBL31510701 0.74 ACHE (0.59) HPGDALDH1A1KDM4EACHEMAOB
SCHEMBL86279 0.74 ACHE (0.59) HPGDALDH1A1KDM4EACHEMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 917 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110527317-B Preparation method of fluorescent red solvent pigment 湖北彩德新材料科技有限公司 2021-06-08 CN claimed
WO-2020028666-A1 TRANSITION TO TRANSLUCENT SUTURES UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2020-02-06 WO claimed
US-20150139908-A1 LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD CANON KK (JP) 2015-05-21 US claimed
EP-2370110-A1 LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD Canon Kabushiki Kaisha (JP) 2011-10-05 EP claimed
US-20110236310-A1 LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD CANON KABUSHIKI KAISHA (JP) 2011-09-29 US claimed
WO-2010074325-A1 LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD CANON KABUSHIKI KAISHA (JP) 2010-07-01 WO claimed
JP-2010508092-A 2010-03-18 JP claimed
EP-2077900-A2 METHODS AND SYSTEMS FOR IMMOBILIZING CORNEAL PROSTHESES SHIUEY, Yichieh (US) 2009-07-15 EP claimed
WO-2008103754-A2 AESTHETIC INTRAOCULAR IMPLANT TSENG JANET C (US) 2008-08-28 WO claimed
WO-2008055118-A2 METHODS AND SYSTEMS FOR IMMOBILIZING CORNEAL PROSTHESES SHIUEY YICHIEH (US) 2008-05-08 WO claimed
EP-0410654-A2 Light- sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1991-01-30 EP claimed
EP-0138543-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1990-12-27 EP claimed
EP-0397435-A1 Near infrared antihalation dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-11-14 EP claimed
US-4879204-A HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1989-11-07 US claimed
US-4851321-A HYDRAZINE DERIVATIVE, HETEROCYCLIC CONTRAST ENHANCER FUJI PHOTO FILM CO., LTD. (JP) 1989-07-25 US claimed
US-4801525-A CYANINE DYES, LIGHT-INSENSITIVE HYDROPHILIC COLLOID LAYER FUJI PHOTO FILM CO., LTD. (JP) 1989-01-31 US claimed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US claimed
EP-0267598-A2 Superhigh contrast negative-type silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-05-18 EP claimed
US-4536473-A Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-08-20 US claimed
EP-0138543-A2 Silver halide photographic light sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110236310-A1 LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD ALDH1A2, PDE6C, CHAT HPGD 1435/4885ALDH1A1 225/4885KDM4E 4492/4885
US-20150139908-A1 LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD ALDH1A2, PDE6C, CHAT HPGD 1435/4885ALDH1A1 225/4885KDM4E 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.