Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30300538 | 0.81 | MAPK1 (0.69) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL8687140 | 0.78 | KMT2A (0.65) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL3606993 | 0.75 | KMT2A (0.54) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| Nitrous Acid SCHEMBL5998440 | 0.74 | KMT2A (0.60) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL27245351 | 0.73 | NR1H3 (0.64) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL29944893 | 0.73 | NR1H3 (0.64) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL8123409 | 0.73 | KMT2A (0.68) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| Nitric Acid SCHEMBL1927242 | 0.72 | NPSR1 (0.59) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL6793571 | 0.72 | RAB9A (0.76) | MAPK1HSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL7533552 | 0.72 | NR1H3 (0.57) | MAPK1HSD17B10RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63284170-A | — | — | None | — | — | JP | disclosed |
| JP-S63284170-A | NOVEL GUANIDINOMETHYL-THIOPHENECARBOXYLIC ACID DERIVATIVE | NIPPON REDARII KK | 1988-11-21 | — | — | JP | disclosed |