Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 4/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SREBF1 | P36956 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533940 | 0.90 | RAB9A (0.56) | SMN1; SMN2LMNASREBF1RAB9APOLB | |
| SCHEMBL7537211 | 0.87 | KMT2A (0.55) | POLBPKMALDH1A1KMT2ACASP3 | |
| SCHEMBL7537015 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNARAB9ANPC1MAPT | |
| SCHEMBL27245351 | 0.84 | NR1H3 (0.64) | NR1H3NR1H2HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL29944893 | 0.84 | NR1H3 (0.64) | NR1H3NR1H2HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL1726857 | 0.81 | LMNA (0.76) | SMN1; SMN2LMNARAB9APOLBPKM | |
| SCHEMBL7569195 | 0.80 | MEN1 (0.49) | LMNATSHRALDH1A1KMT2ACASP3 | |
| SCHEMBL30300538 | 0.80 | MAPK1 (0.69) | NR1H3NR1H2HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL7532757 | 0.80 | TSHR (0.65) | HSD17B10MAPK1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7533623 | 0.79 | ACLY (0.55) | MAPK1SMN1; SMN2LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |