Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 11/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | STAT1 | P42224 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27245351 | 0.82 | NR1H3 (0.64) | MAPK1HSD17B10RAB9APKMPOLB | |
| SCHEMBL29944893 | 0.82 | NR1H3 (0.64) | MAPK1HSD17B10RAB9APKMPOLB | |
| SCHEMBL10613653 | 0.81 | MAPK1 (0.57) | MAPK1HSD17B10RAB9APKMPOLB | |
| SCHEMBL6793571 | 0.80 | RAB9A (0.76) | MAPK1HSD17B10RAB9APKMPOLB | |
| SCHEMBL7533552 | 0.80 | NR1H3 (0.57) | MAPK1HSD17B10RAB9APKMPOLB | |
| SCHEMBL29944956 | 0.79 | NR1H3 (0.63) | MAPK1HSD17B10RAB9APOLBNPC1 | |
| SCHEMBL27245384 | 0.79 | NR1H3 (0.63) | MAPK1HSD17B10RAB9APOLBNPC1 | |
| SCHEMBL15183729 | 0.79 | RAB9A (1.00) | MAPK1HSD17B10RAB9APKMPOLB | |
| SCHEMBL30300673 | 0.78 | RAB9A (0.65) | HSD17B10RAB9APKMPOLBNPC1 | |
| SCHEMBL14082936 | 0.78 | MAPK1 (0.71) | MAPK1HSD17B10RAB9APKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028117-A1 | METHODS OF TREATING CDGSH IRON SULFUR DOMAIN 2 INSUFFICIENCY-ASSOCIATED DISORDERS | YEH, TENG-KUANG (US) | 2023-03-02 | — | — | WO | disclosed |