Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002523 | 0.84 | KDM4E (0.52) | MAOACDK5CDK5R1DYRK1AGSK3A | |
| SCHEMBL9768422 | 0.78 | CDK5 (0.50) | MAOACDK5CDK5R1DYRK1AGSK3A | |
| SCHEMBL9709209 | 0.74 | GAA (0.80) | MAOACDK5CDK5R1GAAMEN1 | |
| SCHEMBL5399928 | 0.71 | CDK4 (0.57) | GAAMEN1POLBCASP6KMT2A | |
| SCHEMBL29958262 | 0.71 | GAA (0.63) | MAOACDK5CDK5R1GAAMEN1 | |
| SCHEMBL29958428 | 0.71 | GAA (0.63) | MAOACDK5CDK5R1GAAMEN1 | |
| SCHEMBL20712297 | 0.71 | CDK5 (0.46) | CDK5CDK5R1DYRK1AGSK3AGSK3B | |
| SCHEMBL2299504 | 0.71 | MAOA (1.00) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL29715739 | 0.71 | MAOA (1.00) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL27066955 | 0.70 | JAK2 (0.50) | MAOACDK5CDK5R1DYRK1AGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63297324-A | — | — | None | — | — | JP | disclosed |
| JP-S63297324-A | REMEDY FOR OSTEOPOROSIS | KISSEI PHARMACEUT CO LTD | 1988-12-05 | — | — | JP | disclosed |