SCHEMBL27066955

SCHEMBL27066955

Oc1ccc2c(c1)[nH]c1ccc3c4ccccc4oc3c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ JAK2 O60674 1/20 0.50
▸ ZAP70 P43403 1/20 0.50
▸ SYK P43405 1/20 0.50
▸ ALOX5 P09917 1/20 0.50
▸ DYRK1A Q13627 3/20 0.49
▸ CDK4 P11802 2/20 0.49
▸ CCND1 P24385 2/20 0.49
▸ CDK5 Q00535 4/20 0.45
▸ CDK5R1 Q15078 3/20 0.45
▸ MAOA P21397 2/20 0.44
▸ GSK3A P49840 1/20 0.44
▸ GSK3B P49841 1/20 0.44
▸ ROCK2 O75116 3/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ CASP6 P55212 1/20 0.41
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31846 0.85 GABRA1 (0.51) JAK2ZAP70SYKDYRK1ACDK4
SCHEMBL29819648 0.85 GABRA1 (0.51) JAK2ZAP70SYKDYRK1ACDK4
SCHEMBL29655467 0.85 GABRA1 (0.51) JAK2ZAP70SYKDYRK1ACDK4
SCHEMBL18646560 0.84 JAK2 (0.45) JAK2ZAP70SYKALOX5DYRK1A
SCHEMBL24728587 0.83 JAK2 (0.53) JAK2ZAP70SYKALOX5DYRK1A
SCHEMBL14992666 0.83 JAK2 (0.44) JAK2ZAP70SYKALOX5CDK4
SCHEMBL4552275 0.83 AHR (0.53) JAK2ZAP70SYKCDK4CCND1
SCHEMBL25689151 0.82 CDK4 (0.51) JAK2ZAP70SYKALOX5CDK4
SCHEMBL19784917 0.81 JAK2 (0.45) JAK2ZAP70SYKALOX5DYRK1A
SCHEMBL15497546 0.80 CDK4 (0.49) JAK2ZAP70SYKALOX5CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 — — US disclosed
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND LAGE3, CRY1, LEF1 JAK2 2813/4885ZAP70 3611/4885SYK 4510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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