Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768414 | 0.93 | ADRB2 (0.47) | ADRB2ADRB1MAPT | |
| SCHEMBL9768407 | 0.85 | RAD52 (0.46) | — | |
| SCHEMBL9768406 | 0.79 | SMN1; SMN2 (0.52) | MAPT | |
| SCHEMBL7332563 | 0.79 | TOP2A (0.55) | ADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL7809148 | 0.79 | ADRB2 (0.64) | ADRB2DNM1ADRB1CYP2D6ADRB3 | |
| SCHEMBL10338976 | 0.78 | ALDH1A1 (0.41) | MAPT | |
| SCHEMBL10614432 | 0.78 | ALDH1A1 (0.45) | MAPT | |
| SCHEMBL10668875 | 0.77 | KCNA3 (0.44) | — | |
| SCHEMBL10667568 | 0.76 | ALDH1A1 (0.51) | — | |
| SCHEMBL9768420 | 0.75 | PARP1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |