Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | TNKS | O95271 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768415 | 0.90 | XDH (0.55) | PARP1SIGMAR1XDHBCHEACHE | |
| SCHEMBL10668875 | 0.85 | KCNA3 (0.44) | XDHBCHEACHE | |
| SCHEMBL10338976 | 0.84 | ALDH1A1 (0.41) | MAOAXDHHTT | |
| SCHEMBL9768407 | 0.83 | RAD52 (0.46) | HTT | |
| SCHEMBL9768404 | 0.81 | XDH (0.56) | PARP1XDHBCHEACHE | |
| SCHEMBL10431239 | 0.80 | CSF1R (0.47) | TNKSCSF1RMAOAHTT | |
| SCHEMBL9781524 | 0.80 | KMT2A (0.42) | HTTBCHEACHE | |
| SCHEMBL9768419 | 0.79 | MAOB (0.59) | PARP1SIGMAR1MAOAXDHBCHE | |
| SCHEMBL10614432 | 0.79 | ALDH1A1 (0.45) | MAOAHTT | |
| SCHEMBL9768410 | 0.79 | ALDH1A1 (0.42) | XDHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2142793-A | — | — | None | — | — | JP | disclosed |
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| JP-H02142793-A | NOVEL BENZOFUROQUINOLINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1990-05-31 | — | — | JP | disclosed |
| EP-0370760-A2 | Benzofuro[3,2-c]quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-05-30 | — | — | EP | disclosed |