Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31589446 | 0.81 | ATM (0.47) | ATMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL5367724 | 0.72 | KDM4E (0.63) | ATMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29101968 | 0.70 | KDM4E (0.46) | ATMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL14714247 | 0.67 | KDM4E (0.43) | ATMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL920293 | 0.67 | LMNA (0.60) | ATMALDH1A1LMNATHRBTSHR | |
| SCHEMBL7557473 | 0.67 | ATM (0.56) | ATMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL5878432 | 0.67 | LMNA (0.49) | ATMALDH1A1LMNAMAPTTHRB | |
| SCHEMBL14696790 | 0.67 | KDM4E (0.47) | ATMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10102699 | 0.66 | LMNA (0.44) | ATMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7034458 | 0.66 | PKM (0.68) | ATMKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63310873-A | — | — | None | — | — | JP | disclosed |
| JP-S63310873-A | 4,5-DINITROIMIDAZOLE DERIVATIVE | TAIHO YAKUHIN KOGYO KK | 1988-12-19 | — | — | JP | disclosed |