Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623079 | 0.86 | FFAR4 (0.70) | CYP1A2CYP3A4CYP2C19CYTH2FFAR4 | |
| SCHEMBL5158966 | 0.80 | CYTH2 (0.57) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL28429355 | 0.79 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL5161240 | 0.78 | CYTH2 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL5160443 | 0.78 | CYTH2 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL2437807 | 0.75 | CYTH2 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11740810 | 0.73 | CRHBP (0.67) | ALDH1A1HPGDTDP1MAPTALOX12 | |
| SCHEMBL2433650 | 0.72 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL7627224 | 0.71 | ALDH1A1 (0.72) | ALDH1A1CYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL11932394 | 0.71 | CRHBP (0.63) | ALDH1A1CYP1A2CYP3A4CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145513-B1 | DERIVATIVES OF DIMETHYL-3-NITRO-4-AMINO-ANILINE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE DYEING OF KERATIN FIBRES | L'OREAL (FR) | 1988-03-23 | — | — | EP | claimed |