Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYTH2 | Q99418 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623079 | 0.87 | FFAR4 (0.70) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL5158966 | 0.81 | CYTH2 (0.57) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL5160443 | 0.79 | CYTH2 (0.54) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL10619263 | 0.78 | ALDH1A1 (0.53) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL2437807 | 0.76 | CYTH2 (0.54) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL11740810 | 0.75 | CRHBP (0.67) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL5161205 | 0.75 | TSHR (0.55) | CYTH2FFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL2433650 | 0.74 | ALDH1A1 (0.51) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL11932394 | 0.72 | CRHBP (0.63) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 | |
| SCHEMBL27876169 | 0.72 | HSP90AA1 (0.50) | CYTH2FFAR4HSP90AA1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | disclosed |
| EP-1757579-A1 | Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | KRT18, DSP, CDC73 | CYTH2 2684/4885FFAR4 3709/4885HSP90AA1 2193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.