SCHEMBL10620161

SCHEMBL10620161

CCN(CC)CCNc1cc([N+](=O)[O-])c(N)c(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.42
ALDH1A1 P00352 5/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPT P10636 5/20 0.39
KAT2B Q92831 4/20 0.39
HCAR3 P49019 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 1/20 0.37
PKM P14618 2/20 0.36
POLB P06746 1/20 0.36
APP P05067 1/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10620266 0.82 KAT2B (0.49) ALDH1A1MAPTKAT2BSMN1; SMN2LMNA
SCHEMBL9498147 0.82 ALDH1A1 (0.48) HDAC1ALDH1A1NPSR1MAPTKAT2B
SCHEMBL10617084 0.81 MAPT (0.48) ALDH1A1MAPTKAT2BHCAR3LMNA
SCHEMBL8355249 0.78 MAPT (0.47) HDAC1ALDH1A1NPSR1MAPTKAT2B
SCHEMBL11316660 0.77 ALDH1A1 (0.53) HDAC1ALDH1A1NPSR1MAPTKAT2B
SCHEMBL8350044 0.77 MAPT (0.46) HDAC1ALDH1A1NPSR1MAPTKAT2B
SCHEMBL10610115 0.75 MAPT (0.50) HDAC1ALDH1A1NPSR1MAPTKAT2B
SCHEMBL8349257 0.75 MAPT (0.44) HDAC1ALDH1A1NPSR1MAPTKAT2B
SCHEMBL14933944 0.75 ALDH1A1 (0.53) HDAC1ALDH1A1NPSR1MAPTKAT2B
SCHEMBL10620887 0.74 ALDH1A1 (0.42) ALDH1A1NPSR1MAPTHCAR3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4736067-A DIRECT AND OXIDATION HAIR DYES L'OREAL (FR) 1988-04-05 US claimed
US-4736067-A DIRECT AND OXIDATION HAIR DYES L'OREAL (FR) 1988-04-05 US disclosed