Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355249 | 0.86 | MAPT (0.47) | ALDH1A1MAPTNPSR1HDAC1LMNA | |
| SCHEMBL11056141 | 0.85 | MAPT (0.54) | ALDH1A1MAPTLMNAKAT2BTSHR | |
| SCHEMBL8350044 | 0.85 | MAPT (0.46) | ALDH1A1MAPTNPSR1HDAC1LMNA | |
| SCHEMBL6151634 | 0.83 | MAPT (0.52) | ALDH1A1MAPTLMNABCHEACHE | |
| SCHEMBL8349257 | 0.83 | MAPT (0.44) | ALDH1A1MAPTNPSR1HDAC1LMNA | |
| SCHEMBL112790 | 0.82 | MAPT (0.54) | ALDH1A1MAPTLMNAKAT2BTSHR | |
| SCHEMBL30808005 | 0.82 | MAPT (0.54) | ALDH1A1MAPTLMNAKAT2BTSHR | |
| SCHEMBL11054352 | 0.82 | MAPT (0.49) | ALDH1A1MAPTLMNATSHRCYP3A4 | |
| SCHEMBL10620161 | 0.82 | HDAC1 (0.42) | ALDH1A1MAPTNPSR1HDAC1LMNA | |
| SCHEMBL29391950 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNAKAT2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4511360-A | Dyeing compositions based on oxidation dyestuff precursors and on nitro benzene dyestuffs and their use for dyeing keratin fibres | L'OREAL (FR) | 1985-04-16 | — | — | US | claimed |
| US-5186717-A | Colorfastness, hair dyes | L'OREAL (FR) | 1993-02-16 | — | — | US | disclosed |
| US-4511360-A | Dyeing compositions based on oxidation dyestuff precursors and on nitro benzene dyestuffs and their use for dyeing keratin fibres | L'OREAL (FR) | 1985-04-16 | — | — | US | disclosed |
| US-4470826-A | HAIR DYES, NITRO DYES, DIRECT DYES | L'OREAL (FR) | 1984-09-11 | — | — | US | disclosed |