Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10449126 | 0.94 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2AATMHTT | |
| SCHEMBL10616528 | 0.90 | L3MBTL1 (0.60) | L3MBTL1MEN1KMT2AATMHTT | |
| SCHEMBL10448919 | 0.87 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AATMHTT | |
| SCHEMBL10449053 | 0.86 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2AATMHTT | |
| SCHEMBL10449070 | 0.84 | LMNA (0.54) | L3MBTL1MEN1KMT2AATMHTT | |
| SCHEMBL10449124 | 0.84 | IDO1 (0.49) | MEN1KMT2AHTTRAB9ALMNA | |
| SCHEMBL10449067 | 0.83 | MMP2 (0.50) | L3MBTL1MEN1KMT2AHTTNPSR1 | |
| SCHEMBL10448707 | 0.81 | KAT6A (0.49) | L3MBTL1MEN1KMT2AATMHTT | |
| SCHEMBL10449154 | 0.78 | EGFR (0.48) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL10448742 | 0.78 | EGFR (0.48) | MEN1KMT2ALMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185387-B1 | NOVEL, N,N'BIS(SULFONYL) HYDRAZINES HAVING ANTINEOPLASTIC ACTIVITY | YALE UNIVERSITY (US) | 1988-12-14 | — | — | EP | disclosed |