SCHEMBL10620309

SCHEMBL10620309

O=C(NCC(O)CO)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 2/20 0.50
ALOX5 P09917 2/20 0.49
PKM P14618 1/20 0.49
GAA P10253 1/20 0.48
ATM Q13315 1/20 0.47
GLA P06280 1/20 0.46
CYP3A4 P08684 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6865356 0.97 GAA (0.51) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL8374395 0.93 GAA (0.48) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL8906782 0.91 CASR (0.48) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL28119673 0.91 GAA (0.44) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL7594424 0.90 GAA (0.46) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL11341597 0.90 CYP3A4 (0.55) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL7591779 0.89 GAA (0.43) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL19032974 0.88 GAA (0.44) ALDH1A1LMNAHTTALOX5PKM
SCHEMBL8377047 0.88 ALOX5 (0.50) ALDH1A1LMNAHTTALOX5GAA
SCHEMBL8380480 0.88 CASR (0.54) ALDH1A1LMNAHTTALOX5PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1988008417-A1 IODIZED BENZENE DIAMINO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND CONTRAST PRODUCTS CONTAINING THEM GUERBET S.A. (FR) 1988-11-03 WO disclosed