Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377047 | 0.92 | ALOX5 (0.50) | CASRMEN1KMT2AHTTNPC1 | |
| SCHEMBL8375515 | 0.90 | CASR (0.49) | CASRMEN1KMT2AHTTNPC1 | |
| SCHEMBL6865356 | 0.88 | GAA (0.51) | MEN1KMT2AHTTSMN1; SMN2MAPT | |
| SCHEMBL10620309 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2AHTTSMN1; SMN2MAPT | |
| SCHEMBL8374395 | 0.84 | GAA (0.48) | MEN1KMT2AHTTSMN1; SMN2MAPT | |
| SCHEMBL28119673 | 0.83 | GAA (0.44) | MEN1KMT2AHTTNPC1S1PR4 | |
| SCHEMBL8906782 | 0.83 | CASR (0.48) | CASRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL7594424 | 0.82 | GAA (0.46) | MEN1KMT2AHTTSMN1; SMN2MAPT | |
| SCHEMBL11341597 | 0.82 | CYP3A4 (0.55) | CASRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL27469454 | 0.81 | ALOX5 (0.67) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782565-B1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-04-07 | — | — | EP | disclosed |
| EP-0782565-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009285-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1996-03-28 | — | — | WO | disclosed |