Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620309 | 0.97 | ALDH1A1 (0.50) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL8374395 | 0.96 | GAA (0.48) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL8906782 | 0.94 | CASR (0.48) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL11341597 | 0.93 | CYP3A4 (0.55) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL28119673 | 0.91 | GAA (0.44) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL19032974 | 0.91 | GAA (0.44) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL8377047 | 0.91 | ALOX5 (0.50) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL28268057 | 0.91 | GAA (0.66) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL7594424 | 0.90 | GAA (0.46) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL7591779 | 0.89 | GAA (0.43) | GAALMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119424692-A | Microcapsule ultrasound contrast agent and preparation method thereof | 郑州大学第一附属医院 | 2025-02-14 | — | — | CN | disclosed |
| CN-113831256-B | Intermediate of iodixanol and method for preparing iodixanol | 江苏宇田医药有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-113968826-B | Preparation method of impurity F and impurity G of iodixanol | 黑龙江迪诺医药有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-116768747-A | Intermediate of ioversol and method for preparing ioversol | 江苏宇田医药有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113968826-A | Preparation method of impurity F and impurity G of iodixanol | 黑龙江迪诺医药有限公司 | 2022-01-25 | — | — | CN | disclosed |
| US-10011560-B2 | Alternative process for the purification of an intermediate in the synthesis of non-ionic X-ray contrast agents | GE HEALTHCARE AS (NO) | 2018-07-03 | — | — | US | disclosed |
| US-9834504-B2 | Alternative process for the purification of an intermediate in the synthesis of non-ionic X-ray contrast agents | GE HEALTHCARE AS (NO) | 2017-12-05 | — | — | US | disclosed |
| US-9834504-B2 | Alternative process for the purification of an intermediate in the synthesis of non-ionic X-ray contrast agents | GE HEALTHCARE AS (NO) | 2017-12-05 | — | — | US | disclosed |
| US-20170253556-A1 | ALTERNATIVE PROCESS FOR THE PURIFICATION OF AN INTERMEDIATE IN THE SYNTHESIS OF NON-IONIC X-RAY CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2017-09-07 | — | — | US | disclosed |
| US-20170253556-A1 | ALTERNATIVE PROCESS FOR THE PURIFICATION OF AN INTERMEDIATE IN THE SYNTHESIS OF NON-IONIC X-RAY CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2017-09-07 | — | — | US | disclosed |
| US-20070203362-A1 | PREPARATION OF IODIXANOL | HOMESTAD OLE M | 2007-08-30 | — | — | US | disclosed |
| EP-1131280-B1 | PREPARATION OF 5-AMINO-ISOPHTHALAMIDES | AMERSHAM HEALTH AS (NO) | 2004-08-11 | — | — | EP | disclosed |
| US-6441235-B1 | DI-LOWER-ALKYL-5-NITROISOPHTHALATE REACTS WITH A DIHYDROXY-MONOALKYLAMINE IN THE PRESENCE OF A BASIC CATALYST AND THEN CATALYLYTICALLY HYDROGENATED, WITHOUT ISOLATING THE 5-NITRO-N,N'-BIS(R)ISOPHTHALAMIDE INTERMEDIATE | AMERSHA, HEALTH AS (NO) | 2002-08-27 | — | — | US | disclosed |
| US-20020095053-A1 | Preparation of 5-amino-isophthalamides | GE HEALTHCARE AS (NO) | 2002-07-18 | — | — | US | disclosed |
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0308364-B1 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AG (DE) | 1993-11-10 | — | — | EP | disclosed |
| US-5073362-A | DICARBOXYLIC ACID-BIS(3,5-DICARBAMOYL-2,4,6-TRIIODOANILIDES) AND X-RAY CONTRAST MEDIA CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0308364-A2 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |
| US-4256729-A | X-RAYS CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4250113-A | 5-SUBSTITUTED N-2,4,6-TRIIODO-N,N'-BIS-(2,3-DIHYDROXYPROPYL) ISOPHTHALAMIDE | NYEGAARD & CO. A/S (NO) | 1981-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011560-B2 | Alternative process for the purification of an intermediate in the synthesis of non-ionic X-ray contrast agents | NISCH, PPIP5K2, IPO4 | GAA 2958/4885LMNA 2318/4885MAPT 3649/4885 |
| US-20020095053-A1 | Preparation of 5-amino-isophthalamides | DNPH1, DDAH1, DOHH | GAA 4260/4885LMNA 2994/4885MAPT 4168/4885 |
| US-20070203362-A1 | PREPARATION OF IODIXANOL | NISCH, HDHD5, INSR | GAA 4282/4885LMNA 3810/4885MAPT 2012/4885 |
| US-20170253556-A1 | ALTERNATIVE PROCESS FOR THE PURIFICATION OF AN INTERMEDIATE IN THE SYNTHESIS OF NON-IONIC X-RAY CONTRAST AGENTS | NISCH, PPIP5K2, IPO4 | GAA 2958/4885LMNA 2318/4885MAPT 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.