Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865356 | 0.91 | GAA (0.51) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL10620309 | 0.91 | ALDH1A1 (0.50) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL8374395 | 0.87 | GAA (0.48) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL8906782 | 0.86 | CASR (0.48) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL7594424 | 0.85 | GAA (0.46) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL11341597 | 0.85 | CYP3A4 (0.55) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL7591779 | 0.84 | GAA (0.43) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL8380480 | 0.83 | CASR (0.54) | GAAATMLMNAHTTALDH1A1 | |
| SCHEMBL8377047 | 0.83 | ALOX5 (0.50) | GAALMNAHTTALDH1A1MEN1 | |
| SCHEMBL19032974 | 0.83 | GAA (0.44) | GAAATMLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106366015-B | A kind of Preparation Method And Their Intermediate of Iopromide | 正大天晴药业集团股份有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-106366015-A | Preparation method and intermediates of iopromide | 正大天晴药业集团股份有限公司 | 2017-02-01 | — | — | CN | disclosed |