SCHEMBL1062043

SCHEMBL1062043

CNOC(=O)/C=C\C(=O)ONC

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.53
KEAP1 Q14145 1/20 0.53
NFE2L2 Q16236 1/20 0.53
ATM Q13315 1/20 0.33
ALDH1A1 P00352 3/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27360648 1.00 HCAR2 (0.53) HCAR2KEAP1NFE2L2ATMALDH1A1
SCHEMBL23544811 0.92 NFE2L2 (0.68) HCAR2KEAP1NFE2L2ALDH1A1KDM4E
SCHEMBL23557517 0.92 NFE2L2 (0.68) HCAR2KEAP1NFE2L2ALDH1A1KDM4E
SCHEMBL28997788 0.87 HCAR2 (0.42) HCAR2KEAP1NFE2L2ALDH1A1MAPT
SCHEMBL11898397 0.86
SCHEMBL11898399 0.86
SCHEMBL25177277 0.80
SCHEMBL27855095 0.79
SCHEMBL7745504 0.77
SCHEMBL25056786 0.77 AKT1 (0.42) HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2964827-B1 VENTILATION INSERT FREUDENBERG CARL KG (DE) 2019-11-06 EP claimed
EP-1161565-B1 USE OF SUPERABSORBENT POLYMERS FOR TREATING RAW SKINS, CORRESPONDING COMPOSITIONS AND METHODS AND RESULTING TREATED SKINS SNF SA (FR) 2009-10-28 EP claimed
US-20260103885-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials GOLD BOND BUILDING PRODUCTS LLC (US) 2026-04-16 US disclosed
US-20250288972-A1 Nanoporous Superabsorbent Particles with Low Non-Solvent Levels KIMBERLY-CLARK WORLDWIDE, INC. 2025-09-18 US disclosed
US-12337297-B2 Nanoporous superabsorbent particles with low non-solvent levels KIMBERLY-CLARK WORLDWIDE, INC. (US) 2025-06-24 US disclosed
WO-2025129030-A1 PROCESS FOR PRODUCING ABSORBENT SUBSTRATES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2025-06-19 WO disclosed
US-20250052057-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2025-02-13 US disclosed
US-12194435-B2 Nanoporous superabsorbent particles KIMBERLY-CLARK WORLDWIDE, INC. (US) 2025-01-14 US disclosed
US-20250001395-A1 Microporous Superabsorbent Material KIMBERLY-CLARK WORLDWIDE, INC. 2025-01-02 US disclosed
US-12152385-B2 Cementitious panels with swellable materials and methods of providing a moisture or water barrier in cementitious panels using swellable materials GOLD BOND BUILDING PRODUCTS, LLC (US) 2024-11-26 US disclosed
US-20240375081-A1 Microporous Superabsorbent Material with Enhanced Surface Area KIMBERLY-CLARK WORLDWIDE, INC. 2024-11-14 US disclosed
EP-0783294-A1 TOPICAL AQUEOUS SKIN CARE COMPOSITION WITH HYDROGEL THICKENER AND WATER INSOLUBLE SILICONE CONDITIONING AGENT THE PROCTER & GAMBLE COMPANY (US) 1997-07-16 EP disclosed
EP-0779804-A1 CLEAR, THICKENED TOPICAL SKIN CARE COMPOSITION WITH WATER-INSOLUBLE PERFUME THE PROCTER & GAMBLE COMPANY (US) 1997-06-25 EP disclosed
WO-1997007779-A1 SKIN CONDITIONING COMPOSITION CONTAINING SILICONE GUM, MIXTURE OF POLYOXYETHYLENES AND GLYCEROL COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1997-03-06 WO disclosed
US-5605681-A POLY-HYDROXY SOLVENT FOR SOAP GELLING AGENT THE PROCTOR & GAMBLE COMPANY (US) 1997-02-25 US disclosed
US-5585092-A USING GLYCEROL AND AN ETHYLENE OXIDE ADDUCT AS SOLVENTS TO REPLACE IRRITATING PROPYLENE GLYCOL; ALSO INCLUDING A SOAP GELLING AGENT OF A FATTY ACID SALT, WATER AND FRAGRANCE; ANTIPERSPIRANTS THE PROCTER & GAMBLE COMPANY (US) 1996-12-17 US disclosed
WO-1996032091-A2 GEL DEODORANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-10-17 WO disclosed
WO-1996014054-A1 TOPICAL AQUEOUS SKIN CARE COMPOSITION WITH HYDROGEL THICKENER AND WATER INSOLUBLE SILICONE CONDITIONING AGENT THE PROCTER & GAMBLE COMPANY (US) 1996-05-17 WO disclosed
WO-1996007395-A1 CLEAR, THICKENED TOPICAL SKIN CARE COMPOSITION WITH WATER-INSOLUBLE PERFUME THE PROCTER & GAMBLE COMPANY (US) 1996-03-14 WO disclosed
US-4076663-A POLYMERIZING WITH UNSATURATED MONOMER, CROSSLINKING, HYDROLYZING SANYO CHEMICAL INDUSTRIES, LTD. (JA) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103885-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials DSG1, AQP4, WAPL HCAR2 4848/4885KEAP1 4377/4885NFE2L2 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.