Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.61 |
| ▸ | BCHE | P06276 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.50 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780466 | 0.79 | ACHE (0.66) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL10654276 | 0.78 | ACHE (0.53) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL9547692 | 0.76 | ACHE (1.00) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL24978304 | 0.75 | HRH3 (0.44) | ACHEMAPK1 | |
| SCHEMBL9583756 | 0.75 | ACHE (0.56) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL25847588 | 0.73 | ACHE (0.70) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL10286039 | 0.71 | ACHE (0.62) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL9634360 | 0.70 | CDC7 (0.49) | ACHEALDH1A1TSHRKDM4ECACNA1B | |
| 7-Hydroxytacrine SCHEMBL9547668 | 0.70 | ACHE (1.00) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL9107151 | 0.69 | ACHE (0.82) | ACHEBCHEALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63225358-A | — | — | None | — | — | JP | disclosed |
| JP-S63225358-A | CYCLOPENTA(B)QUINOLINE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 1988-09-20 | — | — | JP | disclosed |