Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704486 | 0.84 | MDM2 (0.61) | ALDH1A1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL5434510 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRTP53HTTMAPT | |
| Terephthalic Acid SCHEMBL11564620 | 0.79 | TSHR (0.60) | ALDH1A1TSHRTP53HTTMAPT | |
| Terephthalic Acid SCHEMBL2160594 | 0.79 | TSHR (0.60) | ALDH1A1TSHRTP53HTTMAPT | |
| SCHEMBL2289091 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTSMN1; SMN2SRD5A2 | |
| SCHEMBL16553310 | 0.79 | LMNA (0.59) | ALDH1A1TSHRTP53HTTMAPT | |
| SCHEMBL442090 | 0.78 | MDM2 (0.59) | ALDH1A1TSHRHTTMAPTLMNA | |
| Terephthalic Acid SCHEMBL27306913 | 0.78 | TSHR (0.75) | ALDH1A1TSHRTP53SMN1; SMN2SRD5A2 | |
| SCHEMBL5217775 | 0.78 | GSK3B (0.56) | ALDH1A1HTTSMN1; SMN2CA1CA2 | |
| SCHEMBL342966 | 0.78 | GSK3B (0.48) | ALDH1A1HTTMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789724-A | POLYMERIZING ISOLATED AND PURIFIED MIXED DIANHYDRIDES PREPARED BY REACTING ACETIC ANHYDRIDE AND DIACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1988-12-06 | — | — | US | disclosed |