SCHEMBL1062076

SCHEMBL1062076

CCOC(=O)c1ccc(C2=NC(c3ccc(Br)cc3Br)(n3c(-c4ccc(Br)cc4Br)nc(-c4ccc(C(=O)OCC)cc4)c3-c3ccc(C(=O)OCC)cc3)N=C2c2ccc(C(=O)OCC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 3/20 0.39
AKT2 P31751 3/20 0.39
MAPT P10636 4/20 0.39
ATM Q13315 1/20 0.39
NEK2 P51955 1/20 0.39
RARA P10276 2/20 0.38
RARB P10826 2/20 0.38
RARG P13631 2/20 0.38
SIRT2 Q8IXJ6 1/20 0.37
TP53 P04637 1/20 0.35
PDK2 Q15119 1/20 0.35
CYP19A1 P11511 1/20 0.35
TARBP2 Q15633 1/20 0.34
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29893456 1.00 AKT1 (0.39) AKT1AKT2MAPTATMNEK2
SCHEMBL1867195 0.91 MMP2 (0.38) AKT1AKT2MAPTALDH1A1SMN1; SMN2
SCHEMBL1871953 0.86 AKT1 (0.32) AKT1AKT2MAPTTP53ALDH1A1
SCHEMBL1061109 0.86 AKT1 (0.42) AKT1AKT2MAPTATMNEK2
SCHEMBL29604013 0.86 AKT1 (0.42) AKT1AKT2MAPTATMNEK2
SCHEMBL1060659 0.81 AKT1 (0.41) AKT1AKT2MAPTATMNEK2
SCHEMBL29392749 0.81 MGAM (0.34) AKT1AKT2ATM
SCHEMBL476661 0.81 MGAM (0.34) AKT1AKT2ATM
SCHEMBL29892510 0.81 MAPT (0.48) AKT1AKT2MAPTSIRT2SMN1; SMN2
SCHEMBL1079566 0.81 MAPT (0.48) AKT1AKT2MAPTSIRT2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240206322-A1 OPTICAL SEMICONDUCTOR DEVICE, METHOD FOR MANUFACTURING SAME, SOLID-STATE IMAGING DEVICE, AND ELECTRONIC DEVICE KANEKA CORPORATION (JP) 2024-06-20 US disclosed
US-9464172-B2 Alkali-developable curable composition, insulating thin film using the same, and thin film transistor KANEKA CORPORATION (JP) 2016-10-11 US disclosed
US-8809414-B2 Photocurable composition and cured product KANEKA CORPORATION (JP) 2014-08-19 US disclosed
EP-2236543-B1 POLYSILOXANE COMPOUND, ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR KANEKA CORP (JP) 2014-02-26 EP disclosed
EP-2343326-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT Kaneka Corporation (JP) 2011-07-13 EP disclosed
US-7935776-B2 having a carboxy group in its main chain and a acryloyl group in its side chain; Color filters AGI CORPORATION (TW) 2011-05-03 US disclosed
US-20110001190-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR KANEKA CORPORATION (JP) 2011-01-06 US disclosed
EP-2236543-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR Kaneka Corporation (JP) 2010-10-06 EP disclosed
US-7785501-B2 Black resin composition for display device, and member for display device DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-31 US disclosed
US-20080318018-A1 Black Resin Composition for Display Device, and Member for Display Device DAI NIPPON PRINTING CO., LTD. (JP) 2008-12-25 US disclosed
US-20080234403-A1 Radiation curable and developable polyurethane and radiation curable and developable photo resist composition containing the same AGI CORPORATION (TW) 2008-09-25 US disclosed
US-6368774-B1 MIXTURE CONTAINING ISOINDOLININE DYE JSR CORPORATION (JP) 2002-04-09 US disclosed
US-6348298-B1 COMPOSITION CONSISTING OF COLORANT CONTAINING PHTHALOCYANINE BLUE AND PHTHALOCYANINE GREEN OR PIGMENT GREEN 36, ALKALI-SOLUBLE RESIN, POLYFUNCTIONAL MONOMER, AND PHOTOPOLYMERIZATION INITIATOR JSR CORPORATION (JP) 2002-02-19 US disclosed
US-6140019-A Radiation sensitive composition JSR CORPORATION (JP) 2000-10-31 US disclosed
EP-1033626-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
US-6013415-A Radiation sensitive composition JSR CORPORATION (JP) 2000-01-11 US disclosed
EP-0893737-A2 Radiation sensitive composition JSR Corporation (JP) 1999-01-27 EP disclosed
EP-0866367-A2 Radiation sensitive composition JSR Corporation (JP) 1998-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110001190-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR TET1, KDM4A, ASIC1 AKT1 1777/4885AKT2 2472/4885MAPT 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.