SCHEMBL1079566

SCHEMBL1079566

CCOC(=O)c1ccc(C2=NC(c3ccc(Cl)cc3Cl)(n3c(-c4ccc(Cl)cc4Cl)nc(-c4ccc(C(=O)OCC)cc4)c3-c3ccc(C(=O)OCC)cc3)N=C2c2ccc(C(=O)OCC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
NPC1 O15118 1/20 0.48
POLB P06746 1/20 0.48
TSHR P16473 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CNR1 P21554 1/20 0.40
CDC7 O00311 1/20 0.40
DBF4 Q9UBU7 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GABRA2 P47869 5/20 0.38
GABRB2 P47870 5/20 0.38
SLC2A1 P11166 1/20 0.38
DPP4 P27487 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
AKT1 P31749 1/20 0.38
AKT2 P31751 1/20 0.38
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29892510 1.00 MAPT (0.48) MAPTNPC1POLBTSHRRAB9A
SCHEMBL1868574 0.91 MGAM (0.42) MAPTNPC1POLBTSHRRAB9A
SCHEMBL1869270 0.86 MGAM (0.38) MAPTNPC1POLBTSHRRAB9A
SCHEMBL476664 0.86 AKT1 (0.42) MAPTNPC1POLBTSHRRAB9A
SCHEMBL29370507 0.86 AKT1 (0.42) MAPTNPC1POLBTSHRRAB9A
SCHEMBL1061886 0.82 MAPT (0.43) MAPTNPC1POLBTSHRRAB9A
SCHEMBL476565 0.81 HSD11B1 (0.42) NPC1TSHRRAB9ASMN1; SMN2HSD17B10
SCHEMBL29389827 0.81 HSD11B1 (0.42) NPC1TSHRRAB9ASMN1; SMN2HSD17B10
SCHEMBL1062076 0.81 AKT1 (0.39) MAPTPOLBSMN1; SMN2KDM4ESLC2A1
SCHEMBL29893456 0.81 AKT1 (0.39) MAPTPOLBSMN1; SMN2KDM4ESLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240206322-A1 OPTICAL SEMICONDUCTOR DEVICE, METHOD FOR MANUFACTURING SAME, SOLID-STATE IMAGING DEVICE, AND ELECTRONIC DEVICE KANEKA CORPORATION (JP) 2024-06-20 US disclosed
EP-1999514-B1 PHOTOSENSITIVE RESIST COMPOSITION FOR COLOR FILTERS FOR USE IN ELECTRONIC PAPER DISPLAY DEVICES CIBA HOLDING INC (CH) 2018-10-03 EP disclosed
US-9464172-B2 Alkali-developable curable composition, insulating thin film using the same, and thin film transistor KANEKA CORPORATION (JP) 2016-10-11 US disclosed
US-8927182-B2 Photosensitive resist composition for color filters for use in electronic paper display devices BASF SE (DE) 2015-01-06 US disclosed
US-8809414-B2 Photocurable composition and cured product KANEKA CORPORATION (JP) 2014-08-19 US disclosed
EP-2236543-B1 POLYSILOXANE COMPOUND, ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR KANEKA CORP (JP) 2014-02-26 EP disclosed
US-20110237702-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT KANEKA CORPORATION (JP) 2011-09-29 US disclosed
EP-2343326-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT Kaneka Corporation (JP) 2011-07-13 EP disclosed
US-7935776-B2 having a carboxy group in its main chain and a acryloyl group in its side chain; Color filters AGI CORPORATION (TW) 2011-05-03 US disclosed
US-20110001190-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR KANEKA CORPORATION (JP) 2011-01-06 US disclosed
US-6120973-A PHOTOSENSITIVE COMPOSITION AND COLORS WITH POLYMERS JSR CORPORATION (JP) 2000-09-19 US disclosed
EP-1033626-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
EP-1033625-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
US-6087050-A Radiation sensitive composition and color filter JSR CORPORATION (JP) 2000-07-11 US disclosed
US-6013415-A Radiation sensitive composition JSR CORPORATION (JP) 2000-01-11 US disclosed
EP-0902327-A2 Radiation sensitive composition JSR Corporation (JP) 1999-03-17 EP disclosed
EP-0893737-A2 Radiation sensitive composition JSR Corporation (JP) 1999-01-27 EP disclosed
EP-0881541-A1 Radiation sensitive composition and color filter JSR Corporation (JP) 1998-12-02 EP disclosed
EP-0875788-A1 Radiation sensitive composition for color filters JSR Corporation (JP) 1998-11-04 EP disclosed
EP-0866367-A2 Radiation sensitive composition JSR Corporation (JP) 1998-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110001190-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR TET1, KDM4A, ASIC1 MAPT 252/4885NPC1 3909/4885POLB 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.