Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439334 | 0.89 | PNMT (0.53) | SIGMAR1HRH3DRD2HTR1AHTR2A | |
| SCHEMBL6421759 | 0.85 | SIGMAR1 (0.48) | SIGMAR1SLC6A3HTR1A | |
| SCHEMBL8439978 | 0.78 | PNMT (0.56) | SIGMAR1HRH3DRD2HTR1AHTR2A | |
| SCHEMBL6512477 | 0.78 | HRH3 (0.68) | SIGMAR1HRH3DRD2HTR1AHTR2A | |
| SCHEMBL986160 | 0.77 | SIGMAR1 (0.53) | SIGMAR1DRD2 | |
| SCHEMBL8805445 | 0.75 | KDM4E (0.53) | SIGMAR1DRD2HTR1AHTR2A | |
| SCHEMBL8434606 | 0.73 | GRIN2B (0.60) | SIGMAR1 | |
| SCHEMBL8435015 | 0.73 | NPC1 (0.50) | SIGMAR1 | |
| SCHEMBL8440094 | 0.73 | PNMT (0.51) | SIGMAR1SLC6A3HTR1A | |
| SCHEMBL10620955 | 0.72 | MAPT (0.44) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749692-A | COMBINATION OF SULFINPYRAZONE AND PYRIDINE DERIVATIVE | SANOFI, S.A. (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4537894-A | ADMINISTERING SULFINPYRAZONE AND PYRIDINE DERIVATIVE | SANOFI, S.A. (FR) | 1985-08-27 | — | — | US | disclosed |
| US-4464377-A | SYNERGISTIS BETA-ADRENERGIC BLOCKERS AND TICLOPIDINE | SANOFI-SYNTHELABO (FR) | 1984-08-07 | — | — | US | disclosed |