Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 13/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621767 | 0.85 | PTK2 (0.42) | PTK2EPHB4FGFR1FGFR2FGFR4 | |
| SCHEMBL11134269 | 0.75 | PTK2 (0.43) | PTK2EPHB4FGFR1FGFR2FGFR4 | |
| SCHEMBL10621173 | 0.71 | LMNA (0.41) | PTK2KDRLRRK2TNNI3K | |
| SCHEMBL11135444 | 0.70 | PTK2 (0.43) | PTK2EPHB4FGFR1FGFR2FGFR4 | |
| SCHEMBL10621643 | 0.68 | CHAT (0.39) | PTK2AURKBTNNI3K | |
| SCHEMBL11135043 | 0.68 | LMNA (0.39) | PTK2LRRK2TNNI3K | |
| SCHEMBL30738234 | 0.66 | L3MBTL1 (0.39) | — | |
| SCHEMBL741018 | 0.66 | L3MBTL1 (0.39) | — | |
| SCHEMBL14614602 | 0.66 | CA1 (0.38) | PTK2FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL10621640 | 0.65 | CASR (0.44) | PTK2EPHB4LRRK2TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748236-A | Azo dyestuffs having sulpho ortho to azo bridge and containing two triazine reactive groups | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| US-4418015-A | Phthalocyanine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-29 | — | — | US | disclosed |
| EP-0053320-A2 | Process for the preparation of phthalocyanin compounds | BAYER AG (DE) | 1982-06-09 | — | — | EP | disclosed |
| EP-0047863-A2 | Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4280956-A | CONTAINING SULFONAMIDE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |