Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.62 |
| ▸ | CTSK | P43235 | 6/20 | 0.62 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622674 | 1.00 | CTSS (0.62) | CTSSCTSKRENCA2CTSL | |
| SCHEMBL7815002 | 0.91 | REN (0.61) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL11443643 | 0.90 | ITGB3 (0.52) | CTSSCTSKRENCA2CTSL | |
| SCHEMBL11123415 | 0.89 | CTSS (0.62) | CTSSCTSKRENCA2CTSL | |
| SCHEMBL28630396 | 0.89 | CTSS (0.72) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL10144086 | 0.88 | CTSS (0.55) | CTSSCTSKRENCA2CCKBR | |
| SCHEMBL11605396 | 0.88 | CTSS (0.56) | CTSSCTSKRENCA2CTSL | |
| SCHEMBL11606668 | 0.88 | CTSS (0.56) | CTSSCTSKRENCA2CTSL | |
| SCHEMBL11333258 | 0.87 | CTSS (0.59) | CTSSCTSKRENCA2CTSL | |
| SCHEMBL11105884 | 0.87 | ACE (0.61) | CTSSCTSKRENCA2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757153-A | Substituted phenyl group containing pharmaceuticals | G. D. SEARLE & CO. (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0212550-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-04 | — | — | EP | disclosed |