Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.61 |
| ▸ | CTSS | P25774 | 4/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | CCKBR | P32239 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105884 | 0.96 | ACE (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL13093343 | 0.91 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL10622674 | 0.91 | CTSS (0.62) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL10622656 | 0.91 | CTSS (0.62) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL2507079 | 0.90 | REN (0.65) | RENACEBACE1 | |
| SCHEMBL2507078 | 0.90 | REN (0.65) | RENACEBACE1 | |
| SCHEMBL9831759 | 0.90 | CTSS (0.64) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL11682562 | 0.89 | MME (0.59) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL11443643 | 0.89 | ITGB3 (0.52) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL11319244 | 0.89 | REN (0.57) | RENCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |