Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620304 | 0.86 | TDP1 (0.44) | MAPK1TSHRALDH1A1MAPTNPBWR1 | |
| SCHEMBL9526634 | 0.81 | PKM (0.49) | PKMMAPK1CDK4CCND1TSHR | |
| SCHEMBL10609185 | 0.78 | PKM (0.47) | PKMMAPK1CDK4CCND1TSHR | |
| SCHEMBL9526617 | 0.78 | PKM (0.47) | PKMMAPK1CDK4CCND1TSHR | |
| SCHEMBL10623013 | 0.77 | MAPK1 (0.40) | PKMMAPK1CDK4CCND1ALDH1A1 | |
| SCHEMBL10769910 | 0.75 | PKM (0.44) | PKMMAPK1CDK4CCND1TSHR | |
| SCHEMBL9530251 | 0.73 | TDP1 (0.42) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL10565321 | 0.71 | MAPK1 (0.39) | PKMMAPK1CDK4CCND1ALDH1A1 | |
| SCHEMBL10769576 | 0.70 | TDP1 (0.41) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL10559340 | 0.69 | PKM (0.47) | PKMMAPK1ALDH1A1MAPTS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4770692-A | 4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | claimed |