Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526617 | 0.84 | PKM (0.47) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL10609185 | 0.84 | PKM (0.47) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL9526043 | 0.84 | TDP1 (0.50) | PKMMAPK1TSHRALDH1A1MEN1 | |
| SCHEMBL10769910 | 0.81 | PKM (0.44) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL10623535 | 0.81 | PKM (0.47) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL22518610 | 0.75 | PKM (0.67) | PKMMAPK1TSHRALDH1A1MEN1 | |
| SCHEMBL10559340 | 0.75 | PKM (0.47) | PKMMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10604516 | 0.72 | TDP1 (0.50) | PKMMAPK1TSHRALDH1A1POLB | |
| SCHEMBL25216902 | 0.71 | PKM (0.50) | PKMMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL8522013 | 0.71 | GLS (0.50) | PKMMAPK1TSHRALDH1A1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257296-B1 | 4-CYANO(NITRO)-5-OXY(THIO)-PYRAZOLE DERIVATIVES | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0191282-B1 | 1-ARYL-4-NITROPYRAZOLES | BAYER AG (DE) | 1989-10-04 | — | — | EP | disclosed |
| US-4810283-A | PRE- AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-07 | — | — | US | disclosed |
| US-4770692-A | 4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| US-4758673-A | 1-aryl-5-halopyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| EP-0257296-A1 | 4-Cyano(nitro)-5-oxy(thio)-pyrazole derivatives | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| US-4681618-A | 1-aryl-5-halo-4-nitopyrazoles, herbicidal compositions containing them, and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |
| EP-0224094-A2 | 1-Aryl-pyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0191282-A1 | 1-Aryl-4-nitropyrazoles | BAYER AG (DE) | 1986-08-20 | — | — | EP | disclosed |