Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | MPI | P34949 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628276 | 0.88 | L3MBTL1 (0.64) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL18746290 | 0.80 | L3MBTL1 (1.00) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8848964 | 0.76 | NOX4 (0.76) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8848959 | 0.76 | NOX4 (0.76) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL16224301 | 0.76 | NOX4 (0.70) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL15677686 | 0.75 | MEN1 (0.57) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL28485955 | 0.74 | KDM4E (0.56) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17560991 | 0.74 | NOX4 (0.68) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6744649 | 0.73 | GAA (0.71) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3283258 | 0.73 | NOX4 (0.76) | GAAKDM4EL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135713-A2 | Antiviral combinations | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-04-03 | — | — | EP | claimed |
| US-4758572-A | Antiviral combinations | BURROUGHS WELLCOME CO. (US) | 1988-07-19 | — | — | US | disclosed |
| US-4719221-A | ANTIPROTOZOA AGENTS | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |