SCHEMBL3283258

SCHEMBL3283258

NC(=O)NN=Cc1cccc(O)c1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX4 Q9NPH5 1/20 0.76
GAA P10253 5/20 0.71
KDM4E B2RXH2 4/20 0.71
L3MBTL1 Q9Y468 3/20 0.71
LMNA P02545 1/20 0.71
MAPT P10636 1/20 0.71
MPI P34949 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
CTRC Q99895 1/20 0.56
DUSP3 P51452 1/20 0.56
PTPN5 P54829 1/20 0.56
PTPN11 Q06124 1/20 0.56
KMT2A Q03164 1/20 0.55
POLB P06746 1/20 0.55
RAB9A P51151 1/20 0.55
KDM1A O60341 1/20 0.54
MGAM O43451 1/20 0.53
SI P14410 1/20 0.53
MGAM2 Q2M2H8 1/20 0.53
AKR1C3 P42330 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29692908 0.86 CTRC (0.74) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL8764546 0.86 CTRC (0.74) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL14075814 0.86 CTRC (0.74) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL12766495 0.85 NOX4 (0.55) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL6744649 0.83 GAA (0.71) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL6744652 0.83 GAA (0.71) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL18746290 0.83 L3MBTL1 (1.00) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL8848964 0.83 NOX4 (0.76) NOX4GAAKDM4EL3MBTL1LMNA
SCHEMBL8848959 0.83 NOX4 (0.76) NOX4GAAKDM4EL3MBTL1LMNA
Hydrochloric Acid SCHEMBL6843998 0.82 GAA (0.69) NOX4GAAKDM4EL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1438424-B1 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2006-01-18 EP claimed
US-20040259181-A1 detecting beta-D-ribofuranosidase activity using novel chromogenic beta-D-ribofuranoside substrates such as catechol-beta-D-ribofuranoside or 3',4'-dihydroxyflavone-4'-beta-D-dibofuranoside; kits BURTON MICHAEL (GB) 2004-12-23 US claimed
EP-1438424-A2 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY Burton, Michael (GB) 2004-07-21 EP claimed
WO-2003035897-A2 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 WO claimed
US-7709223-B2 Method for detecting bacteria with chromogenic substrates for β-D-ribofuranosidase BURTON MICHAEL 2010-05-04 US disclosed
US-20080193959-A1 Enzyme Substrates BURTON MICHAEL 2008-08-14 US disclosed
US-7384763-B2 Method of detecting β-D-ribofuranosidase activity BURTON MICHAEL 2008-06-10 US disclosed
EP-1438424-B1 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2006-01-18 EP disclosed
US-20040259181-A1 detecting beta-D-ribofuranosidase activity using novel chromogenic beta-D-ribofuranoside substrates such as catechol-beta-D-ribofuranoside or 3',4'-dihydroxyflavone-4'-beta-D-dibofuranoside; kits BURTON MICHAEL (GB) 2004-12-23 US disclosed
EP-1438424-A2 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY Burton, Michael (GB) 2004-07-21 EP disclosed
WO-2003035897-A2 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 WO disclosed