Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140774 | 0.81 | GRIN2D (0.53) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14020980 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9064360 | 0.76 | CYP3A4 (0.32) | TSHRCYP3A4 | |
| SCHEMBL7592620 | 0.73 | TDP1 (0.50) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2581020 | 0.73 | GRIN2D (0.50) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4918988 | 0.72 | TDP1 (0.52) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3816541 | 0.71 | TDP1 (0.48) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2581016 | 0.69 | CYP1A2 (0.62) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2581014 | 0.69 | CYP1A2 (0.57) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28075034 | 0.69 | TDP1 (0.50) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720584-A | Nitro substituted diphenyl ethers and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1988-01-19 | — | — | US | disclosed |
| US-4709004-A | Polyesteramide from hydroxy phenyl-isopropyl-amino diphenyl ether | THE DOW CHEMICAL COMPANY (US) | 1987-11-24 | — | — | US | disclosed |
| US-4689434-A | Nitro substituted diphenyl ethers and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1987-08-25 | — | — | US | disclosed |
| US-4618727-A | Nitro substituted diphenyl ethers | THE DOW CHEMICAL COMPANY (US) | 1986-10-21 | — | — | US | disclosed |