Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14020980 | 0.90 | ALDH1A1 (0.48) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL28420852 | 0.86 | ALDH1A1 (0.54) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL7527476 | 0.86 | CYP1A2 (0.52) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL2581020 | 0.85 | GRIN2D (0.50) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL23214259 | 0.84 | TSHR (0.48) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL31329961 | 0.84 | CYP1A2 (0.50) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL29796101 | 0.84 | TSHR (0.48) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL3981776 | 0.84 | CYP1A2 (0.50) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL6579700 | 0.84 | ALDH1A1 (0.54) | TDP1ALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL6580997 | 0.84 | ALDH1A1 (0.47) | TDP1ALDH1A1TSHRGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254510-B | The synthetic method of 2,4,6-trimethyl m-phenylenediamine | 江苏天嘉宜化工有限公司 | 2018-07-13 | — | — | CN | claimed |
| US-20080227869-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses thereof | MEN TEWA | 2008-09-18 | — | — | US | claimed |
| EP-1232748-B1 | USE OF SUBSTITUTED NITROBENZENE DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY BACTERIA, FUNGI AND VIRUSES | MEN TEWA (CN) | 2006-05-03 | — | — | EP | claimed |
| US-20050228055-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses athereof | MEN TEWA | 2005-10-13 | — | — | US | claimed |
| EP-1232748-A1 | SUBSTITUTED NITROBENZENE DERIVATIVES AS MEDICINES AND OTHER USEFUL USES THEREOF | Men, Tewa (CN) | 2002-08-21 | — | — | EP | claimed |
| WO-1995020637-A2 | HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS | MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) | 1995-08-03 | — | — | WO | claimed |
| CN-114292155-B | Method for purifying mesitylene through thermal coupling | 黄河三角洲京博化工研究院有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114213208-B | Method for extracting, rectifying and purifying mesitylene by high-efficiency composite solvent | 黄河三角洲京博化工研究院有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114292155-A | Method for thermally coupling and purifying mesitylene | 黄河三角洲京博化工研究院有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-114213208-A | Method for extracting, rectifying and purifying mesitylene by using efficient composite solvent | 黄河三角洲京博化工研究院有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-113354543-A | Novel environment-friendly production process for preparing amino product and H-acid by silane chemical reduction of nitro compounds | 深圳有为技术控股集团有限公司 | 2021-09-07 | — | — | CN | disclosed |
| US-10408850-B1 | Method for target substance detection and measurement | HOUND LABS, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| CN-109311889-A | Activin receptor-like kinase inhibitors | 蓝图药品公司 | 2019-02-05 | — | — | CN | disclosed |
| US-4170708-A | FROM AN AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-10-09 | — | — | US | disclosed |
| EP-0000563-A1 | Process for preparing aromatic urethanes | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-02-07 | — | — | EP | disclosed |
| US-4134880-A | Process for producing an aromatic urethane from nitro compounds, hydroxyl compounds and carbon monoxide using metal-Lewis acid-ammonia catalyst systems | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4080365-A | Process for preparing aromatic urethanes | MITSUI TOATSU CHEMICALS (JA) | 1978-03-21 | — | — | US | disclosed |
| US-4070391-A | Process for producing isocyanate from nitro compounds and carbon monoxide using rhodium oxide catalysts | ETHYL CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-4052420-A | PROCESS FOR PRODUCING DIURETHANE FROM DINITRO COMPOUNDS, HYDROXYL COMPOUNDS AND CARBON MONOXIDE | ETHYL CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4052437-A | PROCESS FOR PRODUCING URETHANE FROM NITRO COMPOUNDS, HYDROXYL COMPOUNDS AND CARBON MONOXIDE USING RHODIUM OXIDE CATALYSTS | ETHYL CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227869-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses thereof | NOS3, NOS1, PTGS1 | TDP1 1154/4885ALDH1A1 571/4885TSHR 3651/4885 |
| US-20050228055-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses athereof | APOB, NDUFB1, CYP2F1 | TDP1 1548/4885ALDH1A1 700/4885TSHR 4369/4885 |
| US-10408850-B1 | Method for target substance detection and measurement | CNR1, CNR2, ALK | TDP1 4700/4885ALDH1A1 321/4885TSHR 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.