Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625838 | 0.76 | TLR8 (0.41) | CNR2CNR1TLR8 | |
| SCHEMBL10551830 | 0.72 | L3MBTL1 (0.43) | ADRA2ACNR2CNR1 | |
| SCHEMBL31319669 | 0.66 | TLR8 (0.40) | TLR8 | |
| SCHEMBL9533927 | 0.65 | CYP1A2 (0.41) | ADRA2ASLC2A1 | |
| SCHEMBL7081096 | 0.65 | JAK3 (0.44) | ADRA2ASLC2A1 | |
| SCHEMBL14959689 | 0.64 | TLR8 (0.36) | TLR8 | |
| SCHEMBL6236117 | 0.63 | EPHX2 (0.50) | CNR2CNR1PDE3BPDE3ATLR8 | |
| SCHEMBL10772470 | 0.62 | ALDH1A1 (0.39) | CNR2CNR1 | |
| SCHEMBL5399963 | 0.62 | JAK2 (0.35) | TLR8 | |
| SCHEMBL8997373 | 0.62 | POLB (0.39) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4774254-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |
| EP-0243636-A1 | 1-Aryl-4-trifluoromethyl-5-amino pyrazoles as pesticides | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |