Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476916 | 0.78 | TLR8 (0.41) | TLR8 | |
| SCHEMBL31319669 | 0.76 | TLR8 (0.40) | TLR8 | |
| SCHEMBL6243840 | 0.76 | TLR8 (0.40) | TLR8 | |
| SCHEMBL18921050 | 0.76 | TLR8 (0.40) | TLR8 | |
| SCHEMBL11969241 | 0.76 | TLR8 (0.40) | TLR8 | |
| SCHEMBL11990846 | 0.76 | TLR8 (0.40) | TLR8 | |
| Hydrochloric Acid SCHEMBL5654701 | 0.76 | TLR8 (0.42) | TLR8 | |
| SCHEMBL10630922 | 0.76 | ADRA2A (0.36) | TLR8CNR1CNR2 | |
| SCHEMBL5387962 | 0.72 | SLC9A1 (0.36) | TLR8 | |
| SCHEMBL2073708 | 0.71 | PKM (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243636-A1 | 1-Aryl-4-trifluoromethyl-5-amino pyrazoles as pesticides | BAYER AG (DE) | 1987-11-04 | — | — | EP | claimed |
| US-4774254-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |
| US-4774254-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |
| EP-0243636-A1 | 1-Aryl-4-trifluoromethyl-5-amino pyrazoles as pesticides | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |
| EP-0243636-A1 | 1-Aryl-4-trifluoromethyl-5-amino pyrazoles as pesticides | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |