Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772470 | 0.85 | ALDH1A1 (0.39) | L3MBTL1MAPTALDH1A1TDP1PKM | |
| SCHEMBL10388255 | 0.79 | SMN1; SMN2 (0.38) | MAPTPKMPOLBGAASMN1; SMN2 | |
| SCHEMBL9284026 | 0.79 | SMN1; SMN2 (0.40) | L3MBTL1MAPTALDH1A1TDP1PKM | |
| SCHEMBL10760992 | 0.78 | CNR1 (0.41) | PKMPOLBGAASMN1; SMN2CNR1 | |
| SCHEMBL10388225 | 0.77 | L3MBTL1 (0.41) | L3MBTL1GAASMN1; SMN2CNR1CNR2 | |
| SCHEMBL10775005 | 0.74 | SMN1; SMN2 (0.48) | MAPTALDH1A1PKMPOLBGAA | |
| SCHEMBL10773058 | 0.74 | PKM (0.39) | MAPTALDH1A1PKMGAASMN1; SMN2 | |
| SCHEMBL31319668 | 0.73 | MEN1 (0.38) | MAPTPKMSMN1; SMN2CNR1CNR2 | |
| SCHEMBL10630922 | 0.72 | ADRA2A (0.36) | ADRA2ACNR1CNR2 | |
| SCHEMBL476964 | 0.70 | CNR1 (0.46) | MAPTALDH1A1TDP1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224019-A2 | 1-Aryl-4-nitropyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | claimed |
| US-4810283-A | PRE- AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-07 | — | — | US | disclosed |
| EP-0224019-A2 | 1-Aryl-4-nitropyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |