Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 8/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217925 | 0.89 | TOP2A (0.61) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10330765 | 0.88 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL6217009 | 0.85 | ALDH1A1 (0.60) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10927140 | 0.85 | TOP2A (0.45) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10875671 | 0.84 | TOP2A (0.54) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10625970 | 0.83 | TOP2A (0.61) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL6171288 | 0.83 | TOP2A (0.58) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10330766 | 0.83 | ALDH1A1 (0.63) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL3136282 | 0.83 | TOP2A (0.66) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL9149649 | 0.83 | TOP2A (0.67) | TOP2ATOP2BALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762844-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | claimed |
| EP-0181588-A2 | Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-05-21 | — | — | EP | claimed |
| US-4762844-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0181588-A2 | Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-05-21 | — | — | EP | disclosed |