SCHEMBL1063147

SCHEMBL1063147

O=C(O)CC(O)CCCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 7/20 0.65
MMP13 P45452 6/20 0.65
MMP2 P08253 3/20 0.65
MMP9 P14780 1/20 0.65
MMP14 P50281 1/20 0.65
TRPA1 O75762 2/20 0.64
TRPV1 Q8NER1 1/20 0.56
HDAC3 O15379 1/20 0.55
MAPK1 P28482 1/20 0.55
ADRA1A P35348 1/20 0.55
HDAC4 P56524 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HDAC1 Q13547 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28009949 1.00 MMP12 (0.65) MMP12MMP13MMP2MMP9MMP14
SCHEMBL3877196 0.95 TRPA1 (0.71) MMP12MMP13MMP2MMP9MMP14
SCHEMBL16320515 0.93 TRPA1 (0.74) MMP12MMP13MMP2MMP9MMP14
SCHEMBL687094 0.89 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL4745347 0.89 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL8333817 0.89 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL11252397 0.86 TRPA1 (0.60) MMP12MMP13MMP2MMP9MMP14
SCHEMBL28010005 0.84 MMP12 (0.55) MMP12MMP13MMP2MMP9MMP14
SCHEMBL4552726 0.84 MMP12 (0.55) MMP12MMP13MMP2MMP9MMP14
SCHEMBL5833581 0.84 TRPA1 (0.56) TRPA1TRPV1HDAC3MAPK1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1118629-B1 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KK (JP) 2007-04-25 EP claimed
CN-1260265-C Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2006-06-21 CN claimed
CN-1260266-C Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2006-06-21 CN claimed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-20030180899-A1 Process for producing polyhydroxyalkanoates by utilizing microorganisms HONMA TSUTOMU (JP) 2003-09-25 US claimed
US-6521429-B2 Using culture media and yeast extracts CANON KABUSHIKI KAISHA (JP) 2003-02-18 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
CN-1322768-A Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2001-11-21 CN claimed
CN-1321695-A Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2001-11-14 CN claimed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US claimed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed
EP-2886643-A1 PRODUCTION OF BIOPLASTICS Neol Biosolutions S.A. (ES) 2015-06-24 EP disclosed
US-8658403-B2 Method for producing polyhydroxyalkanoic acid INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2014-02-25 US disclosed
US-20110020886-A1 METHOD FOR PRODUCING POLYHYDROXYALKANOIC ACID INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2011-01-27 US disclosed
JP-2001238669-A MICROORGANISM PRODUCING POLYHYDROXYALKANOATE AND METHOD FOR PRODUCING POLYHYDROXYALKANOATE USING THE MICROORGANISM CANON INC 2001-09-04 JP disclosed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed
JP-2001178486-A METHOD FOR PRODUCING POLYHYDROXYALKANOATE CANON INC 2001-07-03 JP disclosed