Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.71 |
| ▸ | MMP12 | P39900 | 4/20 | 0.63 |
| ▸ | MMP13 | P45452 | 3/20 | 0.63 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.63 |
| ▸ | MMP14 | P50281 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320515 | 0.98 | TRPA1 (0.74) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL28009949 | 0.95 | MMP12 (0.65) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL1063147 | 0.95 | MMP12 (0.65) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL687094 | 0.87 | MMP12 (0.80) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL4745347 | 0.87 | MMP12 (0.80) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL8333817 | 0.87 | MMP12 (0.80) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL10095138 | 0.86 | TRPA1 (0.68) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL6796065 | 0.85 | TRPA1 (0.70) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL29141353 | 0.85 | DPP4 (0.66) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL19682101 | 0.83 | TRPA1 (0.67) | TRPA1TRPV1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527963-B2 | Acetyl-CoA acyltransferase gene disrupted bacterium for producing polyhydroxyalkanoate and method for producing polyhydroxyalkanoate using the same | CANON KABUSHIKI KAISHA (JP) | 2009-05-05 | — | — | US | disclosed |
| EP-1984500-A2 | ADAM10 AND ITS USES RELATED TO INFECTION | VANDERBILT UNIVERSITY (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084488-A2 | ADAM10 AND ITS USES RELATED TO INFECTION | VANDERBILT UNIVERSITY (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20060172399-A1 | Acetyl-CoA acyltransferase gene disrupted bacterium for producing polyhydroxyalkanoate and method for producing polyhydroxyalkanoate using the same | CANON KABUSHIKI KAISHA (JP) | 2006-08-03 | — | — | US | disclosed |
| US-6903233-B2 | Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-07 | — | — | US | disclosed |
| US-20030225301-A1 | Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-12-04 | — | — | US | disclosed |
| EP-1344763-A1 | Process for producing optically active 3-halogenocarboxylic acid esters and 3-azide-carboxylic acid esters | Takasago International Corporation (JP) | 2003-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225301-A1 | Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester | HDHD5, APEH, AOC3 | TRPA1 724/4885MMP12 132/4885MMP13 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.