Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.65 |
| ▸ | MMP12 | P39900 | 3/20 | 0.61 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP14 | P50281 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877196 | 0.98 | TRPA1 (0.71) | TRPA1TRPV1MMP12MMP13MMP2 | |
| SCHEMBL28009949 | 0.93 | MMP12 (0.65) | TRPA1TRPV1MMP12MMP13MMP2 | |
| SCHEMBL1063147 | 0.93 | MMP12 (0.65) | TRPA1TRPV1MMP12MMP13MMP2 | |
| SCHEMBL6796065 | 0.87 | TRPA1 (0.70) | TRPA1TRPV1MMP12MMP13MMP2 | |
| SCHEMBL8333817 | 0.85 | MMP12 (0.80) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL687094 | 0.85 | MMP12 (0.80) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL4745347 | 0.85 | MMP12 (0.80) | TRPA1MMP12MMP13MMP2MMP9 | |
| SCHEMBL19682101 | 0.85 | TRPA1 (0.67) | TRPA1TRPV1MAPTRXFP1S1PR2 | |
| SCHEMBL10095138 | 0.85 | TRPA1 (0.68) | TRPA1TRPV1MMP12MMP13MMP2 | |
| SCHEMBL29141353 | 0.83 | DPP4 (0.66) | TRPA1TRPV1MMP12MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2818562-A1 | Utilization of the novel, environmental isolate Pseudomonas sp. IPB-A36 for the efficient production of mcl/lcl-PHAs and specialty-PHAs | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20140378647-A1 | UTILIZATION OF THE NOVEL, ENVIRONMENTAL ISOLATE PSEUDOMONAS sp. IPB-A36 FOR THE EFFICIENT PRODUCTION OF mcl/lcl-PHAs and SPECIALTY-PHAs | DRITTE PATENTPORTFOLIO BETEILLIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2014-12-25 | — | — | US | disclosed |