Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388964 | 0.84 | MAPT (0.50) | ALDH1A1KDM4EGAADBHHTR1A | |
| SCHEMBL19629677 | 0.81 | PTGS2 (0.58) | ALDH1A1KDM4EGAADBHHTR1A | |
| SCHEMBL6941573 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAADBHHTR1A | |
| SCHEMBL6943761 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4EGAADBHHTR1A | |
| SCHEMBL11845896 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAADBHHTR1A | |
| Hydrochloric Acid SCHEMBL3113761 | 0.77 | KDM4E (0.47) | ALDH1A1KDM4EGAADBHHTR1A | |
| SCHEMBL1706883 | 0.76 | PTGS2 (0.64) | KDM4EHTR2AHTR2CPTGS2MAPT | |
| SCHEMBL29208987 | 0.76 | MAPT (0.42) | ALDH1A1HTR2AHTR2CTTRKMT2A | |
| SCHEMBL4597547 | 0.76 | DHFR (0.41) | ALDH1A1KDM4EGAAHTR2AHTR2C | |
| SCHEMBL4835197 | 0.76 | GAA (0.46) | ALDH1A1KDM4EGAADBHHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105159-A1 | LIGANDS OF THE M6A-RNA READERS | UNIVERSITY OF ZURICH (CH) | 2024-05-23 | — | — | WO | disclosed |
| US-4760180-A | N-terminally substituted dipeptide amides | G. D. SEARLE & CO. (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0213481-A2 | N-terminally substituted dipeptide amides No. 2 | G.D. Searle & Co. (US) | 1987-03-11 | — | — | EP | disclosed |