SCHEMBL4597547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7088043	0.81	MAPT (0.52)	DHFRALDH1A1PTGS2NR3C1NR3C2
	SCHEMBL13304653	0.80	DHFR (0.51)	DHFRALDH1A1PTGS2TUBB4ATUBB
	SCHEMBL8377139	0.78	PTGS2 (0.60)	DHFRALDH1A1PTGS2TUBB1NR3C1
	SCHEMBL29208987	0.76	MAPT (0.42)	ALDH1A1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL1706883	0.76	PTGS2 (0.64)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL23743654	0.76	ALDH1A1 (0.44)	DHFRALDH1A1PTGS2TUBB4ATUBB
	SCHEMBL5828450	0.76	DHFR (0.41)	DHFRALDH1A1PTGS2NR3C1NR3C2
	SCHEMBL14036688	0.76	DHFR (0.45)	DHFRALDH1A1PTGS2NR3C1NR3C2
	SCHEMBL13715424	0.76	DHFR (0.41)	DHFRALDH1A1PTGS2NR3C1NR3C2
	SCHEMBL10632545	0.76	ALDH1A1 (0.46)	ALDH1A1PTGS2MAPTTTRHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.