Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761390 | 0.81 | LMNA (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL28895591 | 0.79 | CHRNB2 (0.32) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5382865 | 0.79 | MEN1 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL16909986 | 0.77 | LMNA (0.50) | CHRNB2CHRNA4CHRNB4LMNA | |
| SCHEMBL11256311 | 0.76 | ALDH1A1 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL10385362 | 0.76 | LMNA (0.53) | LMNA | |
| SCHEMBL1133347 | 0.75 | — | — | |
| SCHEMBL11054719 | 0.74 | PHF8 (0.52) | KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6787736 | 0.73 | LMNA (0.45) | KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL1133346 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137145-B1 | NEW CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1988-04-27 | — | — | EP | disclosed |
| US-4604463-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1986-08-05 | — | — | US | disclosed |