Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385362 | 0.98 | LMNA (0.53) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL19372071 | 0.92 | TSHR (0.45) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11863344 | 0.92 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL10761390 | 0.91 | LMNA (0.39) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL11678191 | 0.90 | LMNA (0.47) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11669181 | 0.90 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL15476221 | 0.90 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL11859487 | 0.90 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL11668562 | 0.90 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL29029253 | 0.90 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559586-B2 | Compositions containing uretdione groups crosslinking at low temperatures | COVESTRO DEUTSCHLAND AG (DE) | 2026-02-24 | — | — | US | disclosed |
| US-20260042877-A1 | ISOCYANATE-TERMINATED PREPOLYMER FOR COATING APPLICATIONS | COVESTRO DEUTSCHLAND AG (DE) | 2026-02-12 | — | — | US | disclosed |
| EP-4631986-A1 | POLYURETHANE PREPOLYMER COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | Mojia (Shanghai) Biotech Co., Ltd (CN) | 2025-10-15 | — | — | EP | disclosed |
| US-20250223395-A1 | NCO-Terminated Prepolymer for Coating Applications | COVESTRO DEUTSCHLAND AG (DE) | 2025-07-10 | — | — | US | disclosed |
| US-12331214-B2 | Resistant 2K-PUR coatings | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2025-06-17 | — | — | US | disclosed |
| US-20250043146-A1 | MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARTATE COATINGS | COVESTRO DEUTSCHLAND AG (DE) | 2025-02-06 | — | — | US | disclosed |
| EP-4499723-A1 | ISOCYANATE-TERMINATED PREPOLYMER FOR COATING APPLICATIONS | Covestro Deutschland AG (DE) | 2025-02-05 | — | — | EP | disclosed |
| EP-4499722-A1 | NCO-TERMINATED PREPOLYMER FOR COATING APPLICATIONS | Covestro Deutschland AG (DE) | 2025-02-05 | — | — | EP | disclosed |
| EP-4453107-A1 | MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARATE COATINGS | Covestro Deutschland AG (DE) | 2024-10-30 | — | — | EP | disclosed |
| US-20240294798-A1 | Coating Agents and Coatings That Are Obtainable Therefrom and Have Improved Resistance to Soiling and (Self-) Cleaning Properties | COVESTRO DEUTSCHLAND AG (DE) | 2024-09-05 | — | — | US | disclosed |
| US-9637506-B2 | Isocyanatosilanes with thiourethane structure | COVESTRO DEUTSCHLAND AG (DE) | 2017-05-02 | — | — | US | disclosed |
| US-20170114082-A1 | ISOCYANATOSILANES WITH THIOURETHANE STRUCTURE | COVESTRO DEUTSCHLAND AG (DE) | 2017-04-27 | — | — | US | disclosed |
| US-9567313-B2 | Isocyanate-functional cyclic carbonates | COVESTRO DEUTSCHLAND AG (DE) | 2017-02-14 | — | — | US | disclosed |
| US-9556304-B2 | Binder with cyclic carbonate structures | COVESTRO DEUTSCHLAND AG (DE) | 2017-01-31 | — | — | US | disclosed |
| US-20160340372-A1 | SILANE-MODIFIED FORMAMIDES | COVESTRO DEUTSCHLAND AG (DE) | 2016-11-24 | — | — | US | disclosed |
| US-9353210-B2 | Silane functional binder with thiourethane structure | COVESTRO DEUTSCHLAND AG (DE) | 2016-05-31 | — | — | US | disclosed |
| US-20150259461-A1 | SILANE FUNCTIONAL BINDER WITH THIOURETHANE STRUCTURE | COVESTRO DEUTSCHLAND AG (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150246936-A1 | ISOCYANATOSILANES WITH THIOURETHANE STRUCTURE | BAYER MATERIALSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| US-20150225363-A1 | ISOCYANATE-FUNCTIONAL CYCLIC CARBONATES | COVESTRO DEUTSCHLAND AG (DE) | 2015-08-13 | — | — | US | disclosed |
| US-20150203623-A1 | BINDER WITH CYCLIC CARBONATE STRUCTURES | COVESTRO DEUTSCHLAND AG (DE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559586-B2 | Compositions containing uretdione groups crosslinking at low temperatures | URB2, UQCRB, UQCRC2 | LMNA 1319/4885MAPT 2543/4885MAPK1 3457/4885 |
| US-20160340372-A1 | SILANE-MODIFIED FORMAMIDES | PFAS, ITGA8, CAD | LMNA 546/4885MAPT 520/4885MAPK1 4290/4885 |
| US-20260042877-A1 | ISOCYANATE-TERMINATED PREPOLYMER FOR COATING APPLICATIONS | GMNN, PUF60, FGB | LMNA 331/4885MAPT 1814/4885MAPK1 3902/4885 |
| US-20150246936-A1 | ISOCYANATOSILANES WITH THIOURETHANE STRUCTURE | ICAM1, ICMT, ABHD5 | LMNA 3762/4885MAPT 2163/4885MAPK1 4630/4885 |
| US-20150225363-A1 | ISOCYANATE-FUNCTIONAL CYCLIC CARBONATES | C9, ALKBH3, APEH | LMNA 1683/4885MAPT 3828/4885MAPK1 3863/4885 |
| US-20170114082-A1 | ISOCYANATOSILANES WITH THIOURETHANE STRUCTURE | ICAM1, ICMT, ABHD5 | LMNA 3762/4885MAPT 2163/4885MAPK1 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.