Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 1/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396957 | 0.79 | MEN1 (0.40) | MAPTMEN1KMT2ARHOCRHOA | |
| SCHEMBL18600038 | 0.78 | GABRP (0.36) | MAPTLMNAPOLBGAAL3MBTL1 | |
| SCHEMBL9419742 | 0.71 | MAPT (0.37) | HTR2ASLC6A4MAPTMEN1KMT2A | |
| SCHEMBL11765293 | 0.71 | MAPT (0.42) | MAPTMEN1KMT2ACYP2A6MPO | |
| SCHEMBL9364439 | 0.70 | SLC6A4 (0.41) | HTR2ASLC6A4MAPTMEN1KMT2A | |
| SCHEMBL10395952 | 0.69 | CYP2C8 (0.40) | — | |
| SCHEMBL29179953 | 0.68 | SLC6A4 (0.43) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL18602316 | 0.68 | IDO1 (0.40) | SLC6A4MAPTMEN1KMT2ARXRA | |
| SCHEMBL30858772 | 0.68 | SLC6A4 (0.43) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL7097948 | 0.67 | MRGPRX4 (0.33) | HTR2ASLC6A4KCNH2CYP2A6RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260924-A1 | Antiinflammatory derivatives of 3-aryl-2,1-benzisoxazole | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-03-23 | — | — | EP | disclosed |